| 摘要 |
PROBLEM TO BE SOLVED: To provide a method of preventing or treating a recurrence of acute otitis media in a subject at risk.SOLUTION: A method of preventing or treating a recurrence of acute otitis media in a subject at risk comprises administering, at least once to the subject, a therapeutically effective amount of a composition comprising at least one immunogenic polypeptide selected from the group consisting of Streptococcus pneumoniae PhtD, PhtE, PcpA, LytB and detoxified pneumolysis, or an immunogenic fragment of them.SELECTED DRAWING: None |
