发明名称 |
SELF-TARGETING GENOME EDITING SYSTEM |
摘要 |
The present disclosure is directed, in some embodiments, to engineered nucleic acids comprising a promoter operably linked to a nucleotide sequence encoding a guide ribonucleic acid (gRNA) that comprises a specificity determining sequence (SDS) and a protospacer adjacent motif (PAM). The present disclosure is directed, in some embodiments, to cells comprising, vectors comprising, and methods of producing the engineered nucleic acids. |
申请公布号 |
WO2016183438(A8) |
申请公布日期 |
2016.12.15 |
申请号 |
WO2016US32348 |
申请日期 |
2016.05.13 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
LU, Timothy, Kuan-Ta;PERLI, Samuel, David;CUI, Hao |
分类号 |
C12N15/00;C12N15/63;G06N3/12 |
主分类号 |
C12N15/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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