| 摘要 |
PROBLEM TO BE SOLVED: To provide a producing method of a tablet inhibited transition from α type crystal to &bgr; type crystal, the tablet being a solid preparation containing the α type crystal of imatinib mesilate.SOLUTION: A producing method of a solid preparation inhibited transition to &bgr; type crystal during formulation and preservation by coating a solid preparation such as a granule and an uncoated tablet containing the α type crystal of imatinib mesilate with a polymer compound with high moistureproofness such as polyvinyl acrylate. The polymer compound with high moistureproofness is particularly preferably a polyvinyl alcohol/acrylic acid/methyl methacrylate copolymer. |
