发明名称 |
DETERMINATION OF SFLT-1:ANGIOGENIC FACTOR COMPLEX |
摘要 |
Methods for determining the presence or amount of a complex comprising a first and second molecular entity are provided, preferably an sFlt-1:PlGF complex. A determination of the presence or amount of the complex can be used in methods for predicting, detecting, monitoring a disease, or guiding therapy in respect to a disease such as vascular, vascular-related disease, cardiac, cardiac-related disease, cancer, cancer-related disease, preeclampsia, and preeclampsia-related disease. Determining sFlt-1:angiogenic factor complex is particularly useful for predicting and detecting preeclampsia in early stages of gestation and in stages of the disease where clinical evaluation may be uninformative. |
申请公布号 |
EP2235529(B1) |
申请公布日期 |
2016.12.14 |
申请号 |
EP20090700404 |
申请日期 |
2009.01.07 |
申请人 |
ORTHO-CLINICAL DIAGNOSTICS, INC. |
发明人 |
BASHIRIANS, George;BYRNE, Deborah;GROULX, Sarah;JACKSON, Sharon;LANE-BROWN, Heather;SANKARAN, Banumathi;SCALICE, Edward;YANG, Karen;ZHENG, Jian |
分类号 |
G01N33/53;G01N33/00;G01N33/574;G01N33/68;G01N33/74 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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