发明名称 |
GENE SEQUENCE OF L-RHAMNOSE ISOMERASE HAVING NEW CATALYTIC FUNCTION AND USE THEREOF |
摘要 |
In the rare sugar strategy of Izumoring (Fig. 1), it is intended to establish a reaction system of producing rare sugars of many types by acquiring an isomerase which acts on various rare aldoses and, therefore, is most efficient in producing various rare ketoses. A DNA encoding the following protein (a) or (b). The above- mentioned DNA which is L-rhamnose isomerase derived from Pseudomonas stutzerii. A protein comprising the amino acid sequence represented by SEQ ID NO:2. A process for producing a recombinant protein characterized by culturing a host cell containing an expression system that can express the above-mentioned protein in a medium and collecting a recombinant protein having an L-rhamnose isomerase activity from the thus obtained culture. A method of applying Fig. 1 to the production of a rare sugar characterized in that the location of a target rare sugar in the overall picture of monosaccharides is understood and thus the optimum production pathway on which the above protein is allowed to act is designed. <IMAGE> |
申请公布号 |
EP1589102(B1) |
申请公布日期 |
2016.12.14 |
申请号 |
EP20040701121 |
申请日期 |
2004.01.09 |
申请人 |
Izumoring Co., Ltd.;Matsutani Chemical Industry Co., Ltd. |
发明人 |
IZUMORI, Ken;TAKADA, Goro;TOKUDA, Masaaki |
分类号 |
C12N15/09;C12N15/61;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/90;C12P19/02;C12P19/24 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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