发明名称 |
HIV INHIBITING 5,6-SUBSTITUTED PYRIMIDINES |
摘要 |
HIV replication inhibitors of formula
having HIV (Human Immunodeficiency Virus) replication inhibiting properties, the preparation thereof and pharmaceutical compositions comprising these compounds. In particular the compounds have an improved ability to inhibit the replication of mutant strains, in particular of strains that have become resistant to one or more known NNRTI drugs, which strains are referred to as drug- or multidrug-resistant HIV strains |
申请公布号 |
EP2781510(B1) |
申请公布日期 |
2016.12.14 |
申请号 |
EP20140170114 |
申请日期 |
2007.12.28 |
申请人 |
Janssen Sciences Ireland UC |
发明人 |
Guillemont, Jerôme, Emile, Georges;Mordant, Céline, Isabelle;Schmitt, Benoit, Antoine |
分类号 |
C07D239/48;A61K31/505;A61K31/506;A61P31/18;C07D401/04;C07D401/06;C07D401/12;C07D405/04;C07D405/12;C07D409/04;C07D409/12;C07D417/06 |
主分类号 |
C07D239/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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