| 发明名称 |
METHODS OF TREATING ACUTE T CELL LEUKEMIA |
| 摘要 |
The present invention is directed to methods of treating T-cell acute lymphoblastic leukemia. This method involves selecting a subject having T-cell acute lymphoblastic leukemia and administering, to the selected subject, a therapeutic agent that inhibits CXCR4-CXCL12 signaling at a dosage effective to treat the T-cell acute lymphoblastic leukemia in the subject. A method of inhibiting T-cell acute lymphoblastic leukemia cell proliferation and/or survival is also disclosed. |
| 申请公布号 |
US2016354373(A1) |
申请公布日期 |
2016.12.08 |
| 申请号 |
US201615174449 |
申请日期 |
2016.06.06 |
| 申请人 |
AIFANTIS Iannis;TIKHONOVA Anastasia |
发明人 |
AIFANTIS Iannis;TIKHONOVA Anastasia |
| 分类号 |
A61K31/506;A61K31/4709;A61K31/4427;A61K45/06;A61K31/395 |
主分类号 |
A61K31/506 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating T-cell acute lymphoblastic leukemia in a subject, said method comprising:
selecting a subject having T-cell acute lymphoblastic leukemia and administering, to the selected subject, a therapeutic agent that inhibits CXCR4-CXCL12 signaling at a dosage effective to treat the T cell acute lymphoblastic leukemia in the subject. |
| 地址 |
Brooklyn NY US |
