BETA-LACTAM CHOLESTEROL ABSORPTION INHIBITORS

摘要

The present invention relates to the novel compounds represented by Formula (Ia) or (Ib) and to their pharmaceutical preparations for the treatment of atherosclerosis and cholesterol level reduction.;

主权项

1. A compound of Formula (Ia) or (Ib): wherein R represents
a) hydrogen;b) —C(═O)—C1-6alkyl-C6H4R3, —C(═O)—C1-6alkenyl-C6H4R3 or —C(═O)—C6H4R3;c) —C1-6alkyl-C6H4R3 or —C1-6alkenyl-C6H4R3, wherein said —C1-6alkyl or —C1-6alkenyl is substituted by OH; R1 represents —OH or —OMe; R2 represents a halogen or —OMe; R3 represents hydrogen, a halogen, —OMe, —NO2 or —OH; or a salt thereof.