发明名称 COMPOSITIONS FOR GENERATING IMMUNE TOLERANCE BY TARGETING ERYTHROCYTES
摘要 Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.
申请公布号 US2016354453(A1) 申请公布日期 2016.12.08
申请号 US201615232714 申请日期 2016.08.09
申请人 École Polytechnique Fédérale de Lausanne (EPFL) 发明人 Hubbell Jeffrey A.;Kontos Stephan;Dane Karen Y.
分类号 A61K39/00;C07K7/08;C07K14/74;A61K9/107;A61K9/51;C12N9/82;C07K16/28 主分类号 A61K39/00
代理机构 代理人
主权项 1. (canceled)
地址 Lausanne CH