发明名称 |
NOVEL THERAPEUTICS FOR THE TREATMENT OF GLAUCOMA |
摘要 |
The present invention provides benzothiadiazine and chroman derivatives and particularly diazoxide and cromakalim derivatives for use in treating glaucoma, retinopathy, treating age related macular degeneration, treating, stabilizing and/or inhibiting blood and lymph vascularization, and reducing intraocular pressure by administering a pharmaceutically effective amount of a prodrug disposed in an ophthalmically acceptable carrier to the eye, wherein the prodrug specifically modulates a KATP channel to reduce an intraocular pressure. |
申请公布号 |
EP3099304(A1) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20150743644 |
申请日期 |
2015.01.30 |
申请人 |
Mayo Foundation for Medical Education and Research;Regents of the University of Minnesota |
发明人 |
FAUTSCH, Michael, P.;DOSA, Peter;WALTERS, Michael, A.;GEORG, Gunda, I. |
分类号 |
A61K31/549 |
主分类号 |
A61K31/549 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|