发明名称 |
METHOD FOR REDUCING WHITE MATTER LESIONS, WHITE MATTER HYPERINTENSITIES (WMH), LEUKOARAIOSIS OR PERIVENTRICULAR WHITE MATTER DISEASE IN ELDERLY |
摘要 |
The invention pertains to the use of one or more of uridine and cytidine, or salts, phosphates, acyl derivatives or esters thereof in the manufacture of a composition for treating, preventing or reducing the risk of occurrence of white matter lesions, white matter hyperintensities (WMH), Leukoaraiosis or periventricular white matter disease in elderly not suffering from a neurodegenerative disorder, preferably non-demented elderly and elderly not suffering from Alzheimer's Disease. It was found that with the compositions according to the invention Nogo-A protein levels could be controlled, particularly suppressed or reduced. |
申请公布号 |
EP3099327(A1) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20150705382 |
申请日期 |
2015.02.02 |
申请人 |
N.V. Nutricia |
发明人 |
VAN WIJK, Nick;HAGEMAN, Robert Johan Joseph;CANSEV, Mehmet |
分类号 |
A61K45/06;A61K31/14;A61K31/202;A61K31/355;A61K31/375;A61K31/4415;A61K31/519;A61K31/683;A61K31/685;A61K31/7068;A61K31/7072;A61K31/714;A61K33/04;A61P25/00 |
主分类号 |
A61K45/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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