发明名称 PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF BRAIN TUMOR OR TEMODAL-RESISTANT GLIOBLASTOMA MULTIFORM COMPRISING AZATHIOPRINE AS ACTIVE INGREDIENT
摘要 The present invention relates to a pharmaceutical composition for the prevention or treatment of cancer or Temodal resistant glioblastoma multiform comprising azathioprine as an active ingredient. The azathioprine of the present invention is not only effective in inhibiting the growth of glioblastoma multiform, a kind of brain tumor, but also excellent in treating glioblastoma multiform that displays resistance against Temodal (temozolomide), the conventional therapeutic agent for glioblastoma multiform, so that it can be effectively used as an active ingredient of a pharmaceutical composition for the prevention or treatment of such cancer as brain tumor (particularly, glioblastoma multiform) and particularly Temodal resistant glioblastoma multiform.
申请公布号 EP2873419(B1) 申请公布日期 2016.12.07
申请号 EP20130816643 申请日期 2013.07.10
申请人 Korea Research Institute of Chemical Technology;Samsung Life Public Welfare Foundation 发明人 CHO, Heeyeong;CHOI, Gildon;PARK, Woo Kyu;JEONG, Dae Young;KIM, Hyeon Young;LEE, Sunkyung;NAM, Do Hyun;SEOL, Ho Jun
分类号 A61K31/52;A61K31/495;A61P35/00 主分类号 A61K31/52
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