发明名称 |
SINGLE MOLECULE PROTEIN SEQUENCING |
摘要 |
The invention provides a device for determining the type of protein in a liquid, the device comprising (a) an immobilized ATP dependent protease based molecular transporter machine configured to guide a protein that is functionalized with labels through a detection area of a detector, (b) said detector, configured to detect a signal as function of the labels of the labelled amino acids, (c) a processor unit, configured to identify from the detector signal a sequence of amino acids of the functionalized protein, wherein the processor unit is further configured to compare the identified sequence of amino acids with the occurrence of such sequence in a database of proteins and to identify the type of protein. |
申请公布号 |
EP2872898(B1) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20130759843 |
申请日期 |
2013.07.15 |
申请人 |
Technische Universiteit Delft |
发明人 |
JOO, Chirlmin;DEKKER, Cornelis;VAN GINKEL, Hendrika Geertruida Theodora Maria;MEYER, Anne Sara |
分类号 |
C12Q1/37;G01N33/487;G01N33/58;G01N33/68 |
主分类号 |
C12Q1/37 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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