发明名称 |
METHYLATION HAPLOTYPING FOR NON-INVASIVE DIAGNOSIS (MONOD) |
摘要 |
Embodiments disclosed herein provides methods for detecting the presence of a target nucleic acid in a mixture of nucleic acids comprising: performing methylation haplotype analysis on a sample comprising a plurality of nucleic acids; and determining whether said sample includes a methylation haplotype indicative of the presence said target nucleic acid. Embodiments disclosed herein provide methods for detecting tumor in a subject and prenatal detection of fetal chromosomal abnormality using the methods for detecting the presence of a target nucleic acid disclosed herein. Further disclosed are probes and kits for methylation haplotype analysis. |
申请公布号 |
EP3099822(A1) |
申请公布日期 |
2016.12.07 |
申请号 |
EP20150743264 |
申请日期 |
2015.01.29 |
申请人 |
The Regents of the University of California |
发明人 |
ZHANG, Kun |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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