MUTANT GLUTAMATE-CYSTEINE LIGASE AND METHOD FOR MANUFACTURING GAMMA-GLUTAMYL-VALYL-GLYCINE

摘要

A mutant glutamate-cysteine ligase (GSHA) suitable for generating ³-Glu-Val, and a method for producing ³-Glu-Val-Gly using the same are provided. ³-Glu-Val is produced by using a mutant GSHA having a specific mutation with Glu and Val as raw materials, and ³-Glu-Val-Gly is further produced by using ³-Glu-Val and Gly as raw materials. ³-Glu-Val-Gly is produced by using a mutant GSHA having a specific mutation with Glu, Val, and Gly as raw materials.