Biofilm disruptive compositions

摘要

In certain embodiments, the present invention relates to compounds, compositions, and methods for disrupting biofilms. In some embodiments, the compounds and compositions comprise unsaturated long chain alcohols and/or aldehydes, or combinations of such compounds. In further embodiments, the present invention contains therapeutic actives to help reduce and/or eradicate the bacteria in the biofilm once the film is disrupted.

主权项

1. A composition comprising:
i. from about 0.005% to less than 0.5% of a biofilm disruptor selected from the group consisting of 1-decen-3-ol, cis-2-nonen-1-ol, and mixtures thereof; and ii. an orally acceptable carrier in the form of a mouthwash, mouthrinse, toothpaste, tooth gel, dentifrice, breath spray, prophylaxis paste, chewing gum, breath strip, lozenge, or breath mint.