COMPOSITIONS AND METHODS COMPRISING BARD1 AND OTHER BRCA1 BINDING PROTEINS

摘要

Disclosed are several novel genes, identified in screening assays based upon binding to the breast cancer protein, BRCA1. The currently preferred gene and protein, termed BARD1, is a RING protein that interacts with BRCA1. The genes, proteins and other biological materials provided are envisioned for use in various cancer-related diagnostic and therapeutic methods, particularly those connected with breast, ovarian and uterine cancer.