发明名称 Apparatus and method for measuring concentration of hemoglobin using photothermal effect
摘要 The present invention relates to an apparatus for measuring concentration of hemoglobin in blood using a photothermal effect, the apparatus including: a reference light source unit for radiating a reference beam; a photothermal light source unit for radiating a photothermal beam from which the photothermal effect is generated; a cuvette unit for accommodating a collected blood sample thereinto and having first and second reflection layers; and a concentration operation unit for calculating the concentration of hemoglobin by using the phase changes of interference signals generated from the incidence of the reference beam radiated from the reference light source unit onto the first and second reflection layers of the cuvette unit as the photothermal beam radiated from the photothermal light source unit is incident onto the cuvette unit and absorbed by hemoglobin to generate the photothermal effect through the emission of heat.
申请公布号 US9594026(B2) 申请公布日期 2017.03.14
申请号 US201514604691 申请日期 2015.01.24
申请人 INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY 发明人 Joo Chulmin;Yim Jinyeong;Kim Hun;Ryu Su Ho
分类号 G01N21/85;G01N21/17 主分类号 G01N21/85
代理机构 LRK Patent Law Firm 代理人 LRK Patent Law Firm
主权项 1. An apparatus for measuring concentration of hemoglobin in blood using a photothermal effect, the apparatus comprising: a reference light source radiating a reference beam; a photothermal light source radiating a photothermal beam from which the photothermal effect is generated; a cuvette accommodating a collected blood sample thereinto and having first and second reflection layers; and a concentration operator loaded on and executed by a hardware processor and calculating the concentration of hemoglobin by using the phase changes of interference signals generated from the incidence of the reference beam radiated from the reference light source onto the first and second reflection layers of the cuvette unit as the photothermal beam radiated from the photothermal light source is incident onto the cuvette and absorbed by hemoglobin to generate the photothermal effect through the emission of heat, wherein the concentration operator reads the reflected interference signals through a spectrometer, reads absolute values of complex numbers obtained through inverse Fourier transform of the interference signals, finds the path-length having the greatest absolute value, and obtains the phase in the signal of the path-length.
地址 Seoul KR