发明名称 |
Three-dimensional discontinuous entity for cell culturing |
摘要 |
The present invention is related to methods and materials for culturing and transporting stem cells in a three-dimensional culture. The materials comprise cellulose nanofibrils in a form of three-dimensional discontinuous entities in a biocompatible hydrogel. |
申请公布号 |
US9593304(B2) |
申请公布日期 |
2017.03.14 |
申请号 |
US201314430833 |
申请日期 |
2013.09.24 |
申请人 |
UPM-KYMMENE CORPORATION |
发明人 |
Laukkanen Antti;Lou Yan-Ru;Yliperttula Marjo;Kuisma Tytti;Nikander Johanna;Pere Jaakko |
分类号 |
C12N5/02;C12N5/071;C12N5/00;C12N5/0735;C12N5/074 |
主分类号 |
C12N5/02 |
代理机构 |
Nixon Peabody LLP |
代理人 |
Nixon Peabody LLP |
主权项 |
1. A three-dimensional discontinuous entity for culturing of cells comprising
a. an aqueous medium comprising a mixture of a first and second aqueous medium; and b. hydrogel bodies comprising cellulose nanofibrils and/or derivatives thereof suspended in the aqueous medium, the cellulose nanofibrils being obtained from plant-derived, mechanically disintegrated cellulose, wherein the cellulose nanofibrils and/or derivatives thereof are suspended in the aqueous medium, wherein the hydrogel bodies have discontinuous structures, are separate or interconnected, and have different sizes and forms. |
地址 |
Helsinki FI |