发明名称 Three-dimensional discontinuous entity for cell culturing
摘要 The present invention is related to methods and materials for culturing and transporting stem cells in a three-dimensional culture. The materials comprise cellulose nanofibrils in a form of three-dimensional discontinuous entities in a biocompatible hydrogel.
申请公布号 US9593304(B2) 申请公布日期 2017.03.14
申请号 US201314430833 申请日期 2013.09.24
申请人 UPM-KYMMENE CORPORATION 发明人 Laukkanen Antti;Lou Yan-Ru;Yliperttula Marjo;Kuisma Tytti;Nikander Johanna;Pere Jaakko
分类号 C12N5/02;C12N5/071;C12N5/00;C12N5/0735;C12N5/074 主分类号 C12N5/02
代理机构 Nixon Peabody LLP 代理人 Nixon Peabody LLP
主权项 1. A three-dimensional discontinuous entity for culturing of cells comprising a. an aqueous medium comprising a mixture of a first and second aqueous medium; and b. hydrogel bodies comprising cellulose nanofibrils and/or derivatives thereof suspended in the aqueous medium, the cellulose nanofibrils being obtained from plant-derived, mechanically disintegrated cellulose, wherein the cellulose nanofibrils and/or derivatives thereof are suspended in the aqueous medium, wherein the hydrogel bodies have discontinuous structures, are separate or interconnected, and have different sizes and forms.
地址 Helsinki FI