Biofilm resistant polymer materials

摘要

The present invention relates to compounds and materials that reduce the accumulation of microorganisms on a surface by interfering with the attachment of the organisms to the surface. The compounds and materials of the present invention are thus useful in preventing the formation of biofilms. The compounds of the present invention may be either adhered to a surface or integrated within a polymer. Surfaces coated by the present invention are resistant to biofilm formation, in part due to the smoothness of the surface coated with the present invention.

主权项

1. A method of rendering a thermoplastic polymer resistant to biofilm formation comprising:
incorporating said thermoplastic polymer with a curable composition comprising:
a mixture of an alkene-based formulation sufficient to adhere to said substrate surface when polymerized;a polymerizable halogenated aryl compound of structure A: wherein R1, R2, R3, R5, or R6 represents Chlorine, Bromine, Hydrogen, or an organic moiety selected from the group consisting of alkyl, aryl, alcoholic, etheric, thioesteric, esteric, amido, amino, thiol, urethane, and acid anhydride, wherein R4 is a hydrogen, methyl group, or methacrylate, wherein at least one of R1, R2, R3, R5, or R6 is Chlorine or Bromine; and wherein Z represents Oxygen; andproviding an energy source sufficient to polymerize said polymerizable halogenated aryl compound; polymerizing the curable composition into said thermoplastic polymer, such that the curable composition renders the surface of said thermoplastic or thermoset polymer resistant to biofilm formation and having a roughness that approximates electropolished stainless steel.