发明名称 |
CHIMERIC POLYPEPTIDE ASSEMBLY AND METHODS OF MAKING AND USING THE SAME |
摘要 |
The present invention relates to bispecific chimeric polypeptide assembly compositions comprising bulking moieties linked to binding domains by cleavable release segments that, when cleaved are capable of concurrently binding effector T cells with targeted tumor or cancer cells and effecting cytolysis of the tumor cells or cancer cells. The invention also provides compositions and methods of making and using the cleavable chimeric polypeptide assembly compositions. |
申请公布号 |
WO2017040344(A2) |
申请公布日期 |
2017.03.09 |
申请号 |
WO2016US49137 |
申请日期 |
2016.08.26 |
申请人 |
AMUNIX OPERATING INC. |
发明人 |
SCHELLENBERGER, Volker;YANG, Fan;THAYER, Desiree;SIM, Bee-cheng;WANG, Chia-wei |
分类号 |
A61K38/19;A61K38/20 |
主分类号 |
A61K38/19 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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