A SEPARATION MATRIX AND A METHOD OF SEPARATING ANTIBODIES

摘要

The invention discloses a separation matrix comprised of porous spherical particles to which antibody-binding protein ligands have been covalently immobilized, wherein the density of said ligands is in the range of 10.5 - 15 mg/ml and the volume-weighted median diameter of said particles is in the range of 30 - 55 µm. The invention further discloses a method of separation of antibodies by affinity chromatography which employs the said separation matrix within a chromatography column.