发明名称 |
LONG-ACTING COAGULATION FACTORS AND METHODS OF PRODUCING SAME |
摘要 |
Polypeptides comprising at least one carboxy- terminal peptide (CTP) of chorionic gonadotropin attached to the carboxy terminus but not to the amino terminus of a coagulation factor and polynucleotides encoding the same are disclosed. Pharmaceutical compositions and pharmaceutical formulations comprising the polypeptides and polynucleotides of the disclosure and methods of using and producing same are also disclosed. |
申请公布号 |
WO2016203482(A3) |
申请公布日期 |
2017.03.09 |
申请号 |
WO2016IL50645 |
申请日期 |
2016.06.19 |
申请人 |
OPKO BIOLOGICS LTD. |
发明人 |
FIMA, Udi Eyal;HART, Gili |
分类号 |
A61K9/38;A61K9/64;C07K1/107;C12N9/64;C12Q1/56 |
主分类号 |
A61K9/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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