发明名称 MODULATION OF ANGIOPOIETIN-LIKE 3 EXPRESSION
摘要 Provided herein are methods, compounds, and compositions for reducing expression of an ANGPTL3 mRNA and protein in an animal. Also provided herein are methods, compounds, and compositions for reducing plasma lipids, plasma glucose and atherosclerotic plaques in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate any one or more of cardiovascular disease or metabolic disease, or a symptom thereof.
申请公布号 AU2017201078(A1) 申请公布日期 2017.03.09
申请号 AU20170201078 申请日期 2017.02.17
申请人 Ionis Pharmaceuticals, Inc. 发明人 Dobie, Kenneth W.;Lee, Richard;Crooke, Rosanne M.;Graham, Mark J.
分类号 A61K31/7105;A61K48/00;C07H21/02 主分类号 A61K31/7105
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