发明名称 |
AMINOGLYCOSIDE DERIVATIVES AND USES THEREOF IN TREATING GENETIC DISORDERS |
摘要 |
Novel aminoglycosides, represented by Formulae la and lb, as defined in the instant specification, designed to exhibit stop codon mutation readthrough activity, are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic diseases and disorders, such as diseases and disorders associated with stop codon mutations. |
申请公布号 |
WO2017037719(A1) |
申请公布日期 |
2017.03.09 |
申请号 |
WO2016IL50968 |
申请日期 |
2016.09.02 |
申请人 |
ELOXX PHARMACEUTICALS LTD. |
发明人 |
BAASOV, Timor;TUVIA, Shmuel |
分类号 |
C07H15/23;A61K31/7036;A61P7/04;A61P21/00;A61P21/04;C07H15/222;C07H15/224 |
主分类号 |
C07H15/23 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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