SYSTEM AND METHOD FOR REAL-TIME SIMULATION OF PATIENT-SPECIFIC CARDIAC ELECTROPHYSIOLOGY INCLUDING THE EFFECT OF THE ELECTRICAL CONDUCTION SYSTEM OF THE HEART

摘要

A method and system for simulating patient-specific cardiac electrophysiology including the effect of the electrical conduction system of the heart is disclosed. A patient-specific anatomical heart model is generated from cardiac image data of a patient. The electrical conduction system of the heart of the patient is modeled by determining electrical diffusivity values of cardiac tissue based on a distance of the cardiac tissue from the endocardium. A distance field from the endocardium surface is calculated with sub-grid accuracy using a nested-level set approach. Cardiac electrophysiology for the patient is simulated using a cardiac electrophysiology model with the electrical diffusivity values determined to model the Purkinje network of the patient.

主权项

1. A method for patient-specific simulation of cardiac function, comprising:
generating a patient-specific anatomical heart model from cardiac image data of a patient; modeling physical properties of cardiac tissue in the patient-specific anatomical heart model based on a distance of the cardiac tissue from one or more anatomical structures in the patient-specific anatomical heart model; and simulating cardiac function for the patient using a cardiac model with the physical properties modeling based on the distance of the cardiac tissue from the one or more anatomical structures in the patient-specific anatomical heart model.