发明名称 IMPROVED SOLUBILITY FOR TARGET COMPOUNDS
摘要 The present disclosure relates to compounds having an improved solubility thereby increasing their bioavailability, lower dosages, etc. The target compounds, may include but are not limited to, macrophage migration inhibitory factor (MIF) inhibitors, epidermal growth factor receptor (EGRF) inhibitors, kinase inhibitors and prodrugs of alpha4 beta1 and alpha4 beta7 integrin antagonists. An illustrative compound is shown below (Formula I):
申请公布号 WO2017040459(A1) 申请公布日期 2017.03.09
申请号 WO2016US49365 申请日期 2016.08.30
申请人 AUNOVA MEDCHEM LLC 发明人 SIDDURI, Achyutharao
分类号 C07D493/00 主分类号 C07D493/00
代理机构 代理人
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