METHODS AND APPARATUS FOR MULTI-CATHETER TISSUE ABLATION

摘要

Catheter systems, tools and methods are disclosed for the selective and rapid application of DC voltage to drive irreversible electroporation, with the system controller configurable to apply voltages to an independently selected subsets of electrodes, such that voltages of one polarity are applied to a multiplicity of electrodes on a first medical device and voltages of the opposite polarity to a multiplicity of electrodes on a second medical device. The first and second medical devices can be epicardial catheters positioned such that their opposing distal tips are approximately aligned and whose segments with electrodes collectively wrap around the pulmonary veins.

主权项

1. An apparatus, comprising:
a voltage pulse generator configured to produce a pulsed voltage waveform; and an electrode controller configured to be operably coupled to the voltage pulse generator, the electrode controller including a first output port and a second output port, the first output port configured to be operatively coupled to a first medical device including a first plurality of electrodes, the second output port configured to be operatively coupled to a second medical device including a second plurality of electrodes, the electrode controller including a selection module and a pulse delivery module, the selection module configured to select at least a first electrode from the first plurality of electrodes and identify at least the first electrode as an anode, the selection module configured to select at least a second electrode from the second plurality of electrodes and identify at least the second electrode as a cathode, the pulse delivery module configured to deliver a first output signal having a first polarity and being associated with the pulsed voltage waveform to the first output port for application to the first electrode, the pulse delivery module configured to deliver a second output signal having a second polarity opposite the first polarity and being associated with the pulsed voltage waveform to the second output port for application to the second electrode.