发明名称 Oxazoline Polymer Compositions and Use Thereof
摘要 Compositions comprising an oxazoline polymer and optional linkers to carry a variety of molecules.
申请公布号 US2017066879(A1) 申请公布日期 2017.03.09
申请号 US201615352521 申请日期 2016.11.15
申请人 ANP Technologies Inc. 发明人 Yin Ray;Pan Jing;Qin Dujie;Zhang Yubei
分类号 C08G69/48;A61K31/7068;A61K31/4745;A61K47/48;C08G83/00 主分类号 C08G69/48
代理机构 代理人
主权项 1. A functionalized polyoxazoline (POX) polymer composition comprising a first and a second functionalized PDX polymer, wherein each of said first and said second functionalized polymer comprises the formula: In—P-L-M-B, wherein I is an initiator, n≧1, P is a polyoxazoline polymer, L is a first linker comprising at least two amine groups, at least two imino (—NH—) groups or at least an amino group and an imino group, wherein said first linker is attached to said PDX polymer by one of said at least two amine groups, at least two imino (—NH—) groups or at least an amino group and an imino group, M is a second linker and B is a bioactive material;wherein said first and said second functionalized PDX polymer are joined by a disulfide bond.
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