发明名称 |
SOLID PRODRUG FORMS OF 2'-CHLORO-2'-METHYL URIDINE FOR HCV |
摘要 |
Provided herein are compounds, compositions and methods for the treatment of Flaviviridae infections, including HCV infections. In certain embodiments, compounds and compositions of nucleoside derivatives are disclosed, which can be administered either alone or in combination with other anti-viral agents. In certain embodiments, the compounds are solid forms of Compound I: (Compound I) |
申请公布号 |
US2017066795(A1) |
申请公布日期 |
2017.03.09 |
申请号 |
US201515123124 |
申请日期 |
2015.03.05 |
申请人 |
IDENIX PHARMACEUTICALS LLC ;Merck Sharp & Dohme Corp. |
发明人 |
Sulliva-Bolyai John Zoltan;Mayes Benjamin Alexander;Mayers Douglas Lytle;Zhou Xiao-Jian;Moussa Adel M.;Stewart Alistair James;Ganga Sindhura;Shultz Clinton Scott;Lee Alfred |
分类号 |
C07H19/10;A61K9/48;A61K31/7072;A61K9/20 |
主分类号 |
C07H19/10 |
代理机构 |
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代理人 |
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主权项 |
1. A Compound I in a form selected from the group consisting of: Form I, II, III, IV, V, VI, VII, and VIII, wherein Compound I has the following structure: |
地址 |
Cambridge MA US |