THERAPEUTIC COMPOUND FOR PAIN AND SYNTHESIS THEREOF

摘要

The invention provides compounds of Formula XXIII:;;wherein R1 is hydrogen, alkyl, acyl, or silyl, R2 is hydrogen, alkyl, benzyl, acyl, or ester, and R3 is hydrogen, alkyl, an aromatic group, azacyclic, carbocycle, aryl, cycloalkyl, heterocycloalkyl, heterocycle, heteroaryl, heteroalkyl, acyl, or ester, as well as derivatives and stereoisomers, pharmaceutically acceptable salts and derivatives thereof; and methods of making and using such compounds. The invention includes pharmaceutical compositions containing such compounds, and the use of such compounds in methods of treating conditions, diseases, or disorders.

主权项

1. A compound of Formula XXIII: wherein R1 is selected from the group consisting of hydrogen, alkyl, acyl, and silyl; R2 is selected from the group consisting of hydrogen, alkyl, benzyl, acyl, and ester; R3 is selected from the group consisting of hydrogen, alkyl, an aromatic group, azacyclic, carbocycle, aryl, cycloalkyl, heterocycloalkyl, heterocycle, heteroaryl, heteroalkyl, acyl, and ester; or a stereoisomers, pharmaceutically acceptable salt, mixture, or derivative thereof.