| 摘要 |
When an analyst inputs the structure of each of sugar chains supposed to be contained in a sample, a supposed ionic valence, a common product ion m/z, etc., then a precursor m/z calculation unit (301) calculates the m/z of a precursor ion derived from the sugar chain and a method file creation unit (305) creates a method file including MRM transitions. A polyvalent-ion information file creation unit (303) creates a file which links a unique ID of the sugar-chain structure to the precursor ion m/z and the product ion m/z. After completion of a measurement, a chromatogram creation unit (34) makes a mass chromatogram for each MRM transition, and a peak-area addition unit (311) adds up the areas of peaks of the mass chromatograms for the MRM transitions corresponding to the same sugar chain by reference to the linking file. A quantitative-value calculation unit (312) determines the proportion of each sugar chain present, as a quantitative value on the basis of the total value. A quantitative output information creation unit (39) converts the quantitative values into a graph, and the graph is output to a display unit (5). Thus, simultaneous multi-component analysis of a compound which is apt to generate a polyvalent ion, such as a sugar chain, can be made with LC-MS. |
