| 发明名称 |
Antibodies Against Tissue Factor Pathway Inhibitor |
| 摘要 |
The invention relates to antibodies that specifically bind to tissue factor pathway inhibitor (TFPI) and that reduce the clotting time of blood. Such antibodies have utility in the treatment of subjects with a coagulopathy. |
| 申请公布号 |
US2017114147(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201715400366 |
申请日期 |
2017.01.06 |
| 申请人 |
Novo Nordisk A/S |
发明人 |
Hilden Ida;Krogh Berit Olsen;Clausen Jes Thorn;Olsen Ole Hvilsted;Breinholt Jens;Lauritzen Brian;Soerensen Brit Binow |
| 分类号 |
C07K16/38 |
主分类号 |
C07K16/38 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A monoclonal antibody that is capable of specifically binding the K2 domain of TFPI, wherein said antibody is capable of specifically binding an epitope comprising residue R17 of SEQ ID NO: 2. |
| 地址 |
Bagsvaerd DK |
