| 发明名称 |
PLASMA MEMBRANE VESICLES COMPRISING FUNCTIONAL TRANSMEMBRANE PROTEINS |
| 摘要 |
Provided herein are methods and compositions for treating a subject in need thereof comprising administering an effective amount of vesicles with functional transmembrane proteins embedded in the plasma membrane. Also provided herein are methods of restoring gap junctional communication comprising the administration of an effective amount of vesicles. |
| 申请公布号 |
US2017112773(A1) |
申请公布日期 |
2017.04.27 |
| 申请号 |
US201615333137 |
申请日期 |
2016.10.24 |
| 申请人 |
Board of Regents, the University of Texas System |
发明人 |
STACHOWIAK Jeanne;SMYTH Hugh;GADOK Avinash Kaur;FERRATI Silvia;ZHAO Chi |
| 分类号 |
A61K9/50;A61K31/704;A61K31/713 |
主分类号 |
A61K9/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A vesicle comprising a phospholipid membrane wherein the phospholipid membrane comprises a recombinant transmembrane protein and a fusogenic peptide, wherein said protein and peptide are embedded in said membrane. |
| 地址 |
Austin TX US |
