| 发明名称 |
Self-Calibration of Spectra Using Differences in Molecular Weight from Known Charge States |
| 摘要 |
A method of calibrating a mass spectrometer is disclosed comprising mass analysing first ions derived from an analyte molecule, wherein the first ions have a first charge state; determining a first mass or mass to charge ratio of the first ions; mass analysing second ions derived from the analyte molecule, wherein the second ions have a second different charge state and wherein the second ions comprise protonated or adduct variants of the first ions; determining a second mass or mass to charge ratio of the second ions; a determining a calibration correction based upon the first mass or mass to charge ratio and the second mass or mass to charge ratio. |
| 申请公布号 |
US2017125222(A1) |
申请公布日期 |
2017.05.04 |
| 申请号 |
US201515317314 |
申请日期 |
2015.06.12 |
| 申请人 |
Micromass UK Limited |
发明人 |
BROWN Jeffery Mark;MURRAY Paul;RICHARDSON Keith |
| 分类号 |
H01J49/00;H01J49/40 |
主分类号 |
H01J49/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of calibrating a mass spectrometer comprising:
mass analysing first ions derived from an analyte molecule, wherein said first ions have a first charge state; determining a first mass or mass to charge ratio of said first ions; mass analysing second ions derived from said analyte molecule, wherein said second ions have a second different charge state and wherein said second ions comprise protonated or adduct variants of said first ions; determining a second mass or mass to charge ratio of said second ions; and determining a calibration correction based upon said first mass or mass to charge ratio and said second mass or mass to charge ratio. |
| 地址 |
Wilmslow GB |
