POLYMORPHIC FORM OF [5-FLUORO-3-(METHYL)-2-METHYLINDOL-1-YL]-ACETIC ACID

摘要

The invention relates to a polymorphic form of [5-fluoro-3-({2-[(4-fluorobenzene)sulfonyl]pyridin-3-yl}methyl)-2-methylindol-1-yl]-acetic acid which has higher solublity than other forms and is therefore useful for preparing stable pharmacetical formulations.

主权项

1. A polymorphic form of [5-fluoro-3-({2-[(4-fluorobenzene)sulfonyl]pyridin-3-yl}methyl)-2-methylindol-1-yl]-acetic acid (Compound 1), characterised in that it gives an FT-Raman spectrum which is characterised by peaks at 3068±2 cm−1, 3054±2 cm−1, 2976±2 cm−1, 1582±2 cm−1, 1427±2 cm−1, 1298±2 cm−1, 1213±2 cm−1, 1190±2 cm−1, 1164±2 cm−1, 1060±2 cm−1, 956±2 cm−1, 927±2 cm−1, 834±2 cm−1, 700±2 cm−1, 502±2 cm−1, 421±2 cm−1, 401±2 cm−1, 388±2 cm−1, 363±2 cm'1, 353±2 cm−1, 301±2 cm−1, 208±2 cm−1, 116±2 cm−1.