| 发明名称 |
SEPARATION METHOD AND SEPARATION MATRIX |
| 摘要 |
The invention discloses a method of separating a biomolecule from at least one other component in a liquid, comprising a step of contacting said liquid with a separation matrix comprising a solid support and polymer chains bound to said solid support. The polymer chains comprise units derived from a first monomer of structure CH2═CH-L-X, where L is a covalent bond or an alkyl ether or hydroxysubstituted alkyl ether chain comprising 2-6 carbon atoms, and X is a sulfonate or phosphonate group. |
| 申请公布号 |
US2017120232(A1) |
申请公布日期 |
2017.05.04 |
| 申请号 |
US201715407240 |
申请日期 |
2017.01.16 |
| 申请人 |
GE Healthcare BioProcess R&D AB |
发明人 |
Hansson Jesper;Rodrigo Gustav;Soderman Tobias E. |
| 分类号 |
B01J39/26;B01J20/24;B01D15/36;C07K1/22;B01D15/38;B01D15/34;B01J20/26;B01J20/286 |
主分类号 |
B01J39/26 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A separation matrix comprising a solid support and copolymer chains bound to said solid support, wherein said copolymer chains comprise units derived from
a) a first monomer of structure CH2═CH-L-X, where L is a covalent bond or an alkyl ether or hydroxysubstituted alkyl ether chain comprising 2-6 carbon atoms, and X is a sulfonate group and b) an N-vinyl amide,
wherein the molar ratio of the units derived from the first monomer to the units derived from the second non-charged monomer is 0.05 to 5. |
| 地址 |
Uppsala SE |
