| 发明名称 |
MESENCHYMAL STEM CELL-DERIVED EXOSOMES AND THEIR USES |
| 摘要 |
The invention relates to exosomes derived from mesenchymal stem cells and well as isolated populations of said exosomes and method for preparing said isolated exosome populations. The invention also relates to a pharmaceutical composition comprising said exosome or isolated exosome population and their use in a method of treating an immune-mediated inflammatory disease in a subject. |
| 申请公布号 |
US2017119682(A1) |
申请公布日期 |
2017.05.04 |
| 申请号 |
US201615341742 |
申请日期 |
2016.11.02 |
| 申请人 |
TiGenix, S.A.U. |
发明人 |
De La Rosa Olga;Lombardo Eleuterio;Dalemans Wilfried;Garcia Casado Javier;Blazquez Duran Rebeca;Sanchez Margallo Francisco Miguel |
| 分类号 |
A61K9/50;A61K38/17 |
主分类号 |
A61K9/50 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An exosome derived from mesenchymal stem cells (MSCs) characterised in that:
a. it has a molecular weight of at least 3 kDa, and/or b. it has a diameter between 150 and 300 nm and/or c. it comprises thrombospondin-1 (TSP-1). |
| 地址 |
Madrid ES |
