发明名称 PROCESS AND INTERMEDIATES FOR PREPARING POLY(ANHYDRIDE-ESTERS)
摘要 Certain embodiments of the invention provide a method comprising treating a hydroxy-carboxylic acid compound with a compound of formula (I) in the absence of a solvent, to provide a diacid of formula (II), wherein R is a linker molecule; wherein each Y is independently a leaving group; and wherein X is a residue of a biologically active compound.
申请公布号 US2017121267(A1) 申请公布日期 2017.05.04
申请号 US201515318306 申请日期 2015.06.10
申请人 Rutgers, the State University of New Jersey 发明人 Uhrich Kathryn E.;Faig Jonathan J.;Smith Kervin
分类号 C07C67/08 主分类号 C07C67/08
代理机构 代理人
主权项 1. A method comprising treating a hydroxy-carboxylic acid compound: with a compound of formula (I): in the absence of a solvent, to provide a diacid of formula (II): wherein R is a linker molecule; wherein each Y is independently a leaving group; and wherein X is a residue of a biologically active compound.
地址 New Brunswick NJ US