| 发明名称 |
PH-SENSITIVE AND BIOREDUCIBLE POLYMER-VIRUS COMPLEX FOR CANCER TREATMENT |
| 摘要 |
The present invention relates to a pH-sensitive and bioreducible polymer-virus complex which can destroy tumor cells more effectively by increasing the efficiency of virus transduction, to a pH-sensitive and bioreducible polymer, and to a pharmaceutical composition containing the polymer-virus complex. |
| 申请公布号 |
US2017119890(A1) |
申请公布日期 |
2017.05.04 |
| 申请号 |
US201615331619 |
申请日期 |
2016.10.21 |
| 申请人 |
INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY |
发明人 |
YUN Chae Ok;KASALA Dayananda |
| 分类号 |
A01N63/00;C12N7/00;A61K31/713 |
主分类号 |
A01N63/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A pH-sensitive and bioreducible polymer, comprising (i) an escapable portion from immune reactions, (ii) a chargeable portion and (iii) a bioreducible portion including disulfide linkages, and that may be bonded to a surface of virus. |
| 地址 |
Seoul KR |
