| 发明名称 |
METHODS OF MEASURING FACTOR D ACTIVITY AND POTENCY OF FACTOR D INHIBITORS |
| 摘要 |
The invention relates to methods of measuring the activity of Factor D, the key driver in the activation of the alternative complement pathway, methods of determining the potency of Factor D inhibitors, and methods of screening for Factor D inhibitors. |
| 申请公布号 |
US2017122944(A1) |
申请公布日期 |
2017.05.04 |
| 申请号 |
US201615336081 |
申请日期 |
2016.10.27 |
| 申请人 |
GENENTECH, INC. |
发明人 |
ORREN Linda;MILLER Aaron;JIA Xiaoqing;WONG Pin Yee |
| 分类号 |
G01N33/573 |
主分类号 |
G01N33/573 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of measuring the activity of Factor D in a sample derived from a subject, comprising performing a proximity-based measurement assay, wherein the proximity-based measurement assay measures the cleavage of Factor B. |
| 地址 |
South San Francisco CA US |
