发明名称 NITROGEN-CONTAINING HETEROCYCLIC COMPOUND
摘要 The present invention provides a compound having a cholinergic muscarinic M1 receptor positive allosteric modulator activity and useful as a medicament such as a prophylactic or therapeutic drug for Alzheimer's disease, schizophrenia, pain, sleep disorder, Parkinson's disease dementia, dementia with Lewy bodies and the like, and the like. The present invention relates to a compound represented by the formula (I) or a salt thereof.;;wherein each symbol is as described in the attached DESCRIPTION.
申请公布号 US2017121308(A1) 申请公布日期 2017.05.04
申请号 US201515318552 申请日期 2015.06.11
申请人 Takeda Pharmaceutical Company Limited 发明人 OGINO Masaki;KIMURA Eiji;SUZUKI Shinkichi;ASHIZAWA Tomoko;IMAEDA Toshihiro;FUJIMORI Ikuo;ARAI Ryosuke
分类号 C07D401/10;C07D213/81;C07D405/14 主分类号 C07D401/10
代理机构 代理人
主权项 1. A compound represented by the formula (I):wherein A is a cyclic group which is optionally further substituted; R1 is a hydrogen atom or a hydroxyl group; R2 and R3 are each independently a hydrogen atom, a halogen atom, a cyano group, an optionally substituted C1-6 alkyl group, an optionally substituted C2-6 alkenyl group, an optionally substituted C3-6 cycloalkyl group, or an optionally substituted C1-6 alkoxy group; R4 is a hydrogen atom or a halogen atom; R5 is an optionally substituted 5- or 6-membered aromatic heterocyclic group, a halogen atom, a cyano group, an optionally substituted C1-6 alkyl group, or an optionally substituted C1-6 alkoxy group; and X is CH or N,or a salt thereof.
地址 Osaka-shi, Osaka JP