METHOD AND KIT FOR BOWEL PREPARATION

摘要

The present invention provides methods and taste-modifying kits for facilitating cleansing of the gastrointestinal tract of a patient prior to a diagnostic, surgical or therapeutic procedure. The methods and taste-modifying kits can improve patient compliance, and thus, efficacy of the preparation. Specifically, the present methods make the gastrointestinal tract preparation composition palatable for the patient to consume. For example, for a patient preparing to undergo colonoscopy, the present methods make the bowel preparation solution taste significantly less salty.

主权项

1. A taste-modifying kit for red don a salty taste of a liquid composition administered to a subject, the kit comprising: (i) a premeasured amount of at least one pH-modifying agent wherein the amount is sufficient to adjust the pH of the liquid composition to a pH ranging from 1 to 6.9, (ii) miraculin, and (iii) instruction material indicating that the salty taste of the liquid composition is to be reduced by a method comprising the steps of:
(a) determining the pH of the liquid composition, wherein the pH ranges from 1 to 6.9 or is adjusted to range from 1 to 6.9 using the at least one pH-modifying agent; (b) providing miraculin to the subject; and (c) administering orally the liquid composition to the subject after step (b).