METHODS AND COMPOSITIONS FOR DERMATOLOGICAL USE COMPRISING FLUTICASONE AND MOMETASONE AND BIOPOLYMERS

摘要

Disclosed are compositions comprising topical corticosteroids, such as fluticasone and mometasone, and a biopolymer in a cream base, wherein the cream base comprises a primary and a secondary emulsifier, a waxy material, a co-solvent, a preservative, an acid, a chelating agent, a penetration enhancer, a buffering agent, and water. The biopolymer comprises chitosan. The compositions disclosed herein are suitable for the treatment of dermatological conditions including but not limited to healing wounds and treatment of dermatitis.

主权项

1. A composition comprising a topical corticosteroid and a biopolymer in a cream base, wherein the cream base comprises a primary and a secondary emulsifier, a waxy material, a co-solvent, a preservative, an acid, and water;
wherein the topical corticosteroid comprises fluticasone propionate or mometasone furoate.