PHARMACEUTICAL COMPOSITION COMPRISING NON-IONIC SURFACTANTS

摘要

The present invention relates to a pharmaceutical composition comprising poorly soluble compounds such as BSC class II or IV kinase inhibitors, a process for the preparation thereof and its use in the treatment of diseases, in particular cancer, further particularly in non-small lung cancer.

主权项

1. A pharmaceutical composition comprising
a) one or more active ingredients or pharmaceutically acceptable salt thereof, b) a non-ionic surfactant A solid at room temperature, and c) a non-ionic surfactant B liquid at room temperature, wherein the HLB of surfactants A and B are independently equal or greater than 8 and wherein the active ingredients or pharmaceutically acceptable salt thereof are dispersed in the matrix formed by the other ingredients.