| 主权项 |
1. A compound having a structure of formula (I): or a pharmaceutically acceptable salt or prodrug thereof; wherein: Ra is H or is selected from optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, heterocycloalkyl, (cycloalkyl)alkyl, (heterocycloalkyl)alkyl, aryl, heteroaryl, aralkyl, and heteroaralkyl; Rb is H or is selected from optionally substituted alkyl, alkenyl, alkynyl, acyl, —C(O)O(alkyl), and —C(O)O(aryl); each Rc is independently selected from H or alkyl, or two occurrences of R1 are taken together with the intervening —O—B—O— atoms to form an optionally substituted boron-containing ring; X is O or S; R1 and R2 are each independently selected from H and optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, (cycloalkyl)alkyl, heterocycloalkyl, (heterocycloalkyl)alkyl, aryl, heteroaryl, aralkyl, and heteroaralkyl; R1 and R2 are taken together with the intervening atoms to form an optionally substituted 5- to 7-membered ring; and R3 is H or optionally substituted alkyl; or R1 and R3 are taken together with the intervening atoms to form an optionally substituted 5- to 7-membered ring; wherein the compound is not: |
