主权项 |
1. A compound of Formula I or a pharmaceutically acceptable salt thereofwherein:
R1 is:
methyl substituted with i) C4-C6 cycloalkyl optionally substituted with a) one or two F or b) OH; or ii) 5 or 6 membered heterocycloalkyl substituted with C(O)CH3;C2-C3 alkyl substituted with CF3 or —SO2CH3;6 membered heteroaryl containing 1 or 2 N atom, said heteroaryl is optionally substituted with one to two substituents selected from the group consisting of C1-C3 alkyl, halo, CN and methoxy; orphenyl substituted with CN, R2 is C1-C3 alkyl, R3 is halo or CN; R4 is H; R5 is C1-C3 alkyl; R6 is H or methyl, and R7 is selected from the group consisting of.
4 to 6 membered heterocycloalkyl containing 1 N atom, wherein said heterocycloalkyl is optionally substituted with methyl;NRaRb, wherein said Ra is H or methyl, and said Rb is selected from the group consisting of i) methyl substituted with C3-C4 cycloalkyl, ii) C4-C5 cycloalkyl optionally substituted with methyl, and iii) C3-C4 alkyl; andORc, wherein said Rc is i) C4-C5 cycloalkyl; or ii) methyl substituted with C3-C4 cycloalkyl |