Computed tomography breast imaging and biopsy system

摘要

A prone CT breast x-ray imaging system is described that can image a full breast to create a conventional two-dimensional digital image in very high resolution (e.g., ≦25 micron pixels). The system is capable of imaging the entire breast in three-dimensional based on multiple projection views from a one-dimensional or two-dimensional detector. Data can be acquired and reconstructed with a limited number of views from limited angles or with conventional cone beam CT algorithms. The resulting three-dimensional image enables the detection and diagnosis of fine micro calcifications and small masses as may be distributed throughout the breast, thus allowing radiologists to make an improved determination of malignancy as opposed to conventional two-dimensional digital mammography. In addition, the injection of intravenous contrast in conjunction with or without pre and post contrast subtraction imaging provides a radiologist with morphologic information on the existing tumor burden in the breast. This capability may obviate the need for an independent contrast MRI exam of the breast which is increasingly performed for local staging and determination of tumor extent in a patient with a known cancer. Integrated biopsy capability permits convenient and rapid biopsy of any area suspicious for malignancy.

主权项

1. A breast imaging apparatus, comprising:
a locator for positioning a breast of a patient within a predetermined frame of reference having a predetermined axis extending away from a boundary plane of the predetermined frame of reference, wherein an axis of the breast that extends from a chest wall of the patient through a nipple of the breast is alignable with said predetermined axis for imaging; a first support member pivotably mounted to a pedestal, wherein the first support member pivots about the predetermined axis; an imaging beam source mounted to the first support member for transmitting an imaging beam through said predetermined frame of reference; a second support member pivotably mounted to the first support member at an adjoinment location offset from said predetermined axis; an imaging signal detector mounted to the second support member for receiving said imaging beam and providing an output signal in response thereto, wherein said imaging beam source and said imaging signal detector are each moveable relative to said predetermined frame of reference and are moveable relative to one another, wherein said output signal comprises projection image data corresponding with a predetermined angular range of projection views of the breast, and wherein said imaging signal detector comprises: an array of detector elements, comprising an active array of detector elements configured to scan across a region of interest within said predetermined frame of reference, said active array of detector elements having a length defined by at least one column of aligned detector elements extending parallel to said predetermined axis of said predetermined frame of reference and having a width defined by at least one detector element extending in a direction orthogonal to said length, wherein said width of the active array is less than a width of the breast located within said predetermined frame of reference; and, a processor for computed tomography processing said projection image data to provide a reconstructed image.