Effective method of treatment of porcine circovirus and <i>Lawsonia intracellularis </i>infections

摘要

The present invention relates to the use of porcine circovirus type 2 (PCV2) antigen and Lawsonia intracellularis (L. intracellularis) antigen for the prevention, reduction in severity of, lessening of the clinical symptoms associated therewith, reduced incidence in a herd, and treatment of swine against Porcine Circovirus Associated Diseases (PCVAD) and L. intracellularis associated diseases. In particular, the present invention provides a method for the treatment or prophylaxis of an animal against PCV2 infection and ileitis caused by L. intracellularis, or a method for reduction of clinical symptoms caused by or associated with a PCV2 and L. intracellularis infection, comprising the step of administering an effective amount of PCV2 antigen and L. intracellularis antigen to an animal in need of such treatment.

主权项

1. A method for the treatment or prophylaxis of a porcine against PCV2 and Lawsonia intracellularis (L. intracellularis), comprising the step of administering an effective amount of PCV2 ORF2 protein and an effective amount of a modified live L. intracellularis antigen to the porcine, wherein the L. intracellularis antigen has the immunogenic properties of at least one of the L. intracellularis deposits selected from the group consisting of ATCC accession No. PTA-4926 or ATCC accession No. 55783, such that one or more clinical symptoms caused by or associated with PCV2 and L. intracellularis infection and selected from the group consisting of wasting, paleness of skin, unthriftiness, respiratory distress, diarrhea, icterus, jaundice, ileitis, weight loss, and death is reduced as compared to an untreated animal infected with PCV2 and/or L. intracellularis.