Use of 15-benzylidence-14-deoxy-11, 12 -dehyroandrographolide derivative in manufacture of medicaments for protecting liver and anti-hepatitis C virus

摘要

Disclosed is use of andrographolide derivative as shown by general formula 1 in manufacture of medicaments for anti-hepatitis C virus, and preventing and treating immunological liver damage caused by virus infection and different chemical liver damage.;

主权项

1. A method of treating liver damage, comprising administering a dosage form comprising a 15-benzylidene-14-deoxy-11,12-dehydroandrographolide derivative having a structure as shown in Formula 1, selected from the group consisting of the following: A: R1=H, R2=4-Cl—C6H4, R3=R4=H; B: R1=H, R2=C6H5, R3=R4=H; C: R1=H, R2=3-Br—C6H4, R3=R4=H; D: R1=H, R2=4-Cl—C6H4, R3=R4=COR5, R5=3-pyridyl; E: R1=H, R2=4-Cl—C6H4, R3=R4=COR5, R5=CH2CH2COOH.